Category: Ingredients
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Tribulus Terrestris: What’s Actually Proven, According to a 2025 Systematic Review
Tribulus Terrestris: What’s Actually Proven, According to a 2025 Systematic Review 2025 Systematic Review 1 Product Uses It Written by the Health Supplements Lab Editorial Team, drawing on a 2025 systematic review of clinical trials and a randomized controlled trial on symptom outcomes. Last reviewed September 2026 Tribulus Terrestris has been called “one of the…
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Lidocaine and Topical Anesthetics for Premature Ejaculation: One of the Better-Evidenced Categories We Cover
Lidocaine and Topical Anesthetics for Premature Ejaculation: One of the Better-Evidenced Categories We Cover 2,008 Men, 11 RCTs Outperformed Oral Medications Written by the Health Supplements Lab Editorial Team, drawing on two independent meta-analyses and head-to-head trials against oral medications. Last reviewed September 2026 Most of what we cover on this site involves correcting an…
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Selenium: The Real Benefits, and Where the Upper Limit Line Actually Is
Selenium: The Real Benefits, and Where the Upper Limit Line Actually Is Major NIH Trial Reviewed 1 Product Uses a High Dose Written by the Health Supplements Lab Editorial Team, drawing on NIH Office of Dietary Supplements data and the SELECT prostate cancer prevention trial. Last reviewed September 2026 Selenium is a genuinely essential mineral…
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Pterostilbene: Resveratrol’s More Bioavailable Cousin, With a Much Thinner Human Trial Record
Pterostilbene: Resveratrol’s More Bioavailable Cousin, With a Much Thinner Human Trial Record 80% vs. 20% Bioavailability 1 Product Uses It Written by the Health Supplements Lab Editorial Team, drawing on pharmacokinetic research and the primary human safety trial. Last reviewed September 2026 Pterostilbene is often marketed as “the better resveratrol.” The bioavailability claim behind that…
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Cranberry Extract and Prostate Health: What Multiple Studies Actually Show
Cranberry Extract and Prostate Health: What Multiple Studies Actually Show 3 Independent Human Trials 6-Month Trial Duration Written by the Health Supplements Lab Editorial Team, drawing on three independent human trials and one supporting animal study. Last reviewed September 2026 Cranberry is best known for urinary tract infection prevention, but a separate, growing body of…
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Beta-Sitosterol and Prostate Health: The Cochrane Evidence
Beta-Sitosterol and Prostate Health: The Cochrane Evidence 519 Men, 4 Trials 18-Month Follow-Up Data Written by the Health Supplements Lab Editorial Team, drawing on the Cochrane/BJU International systematic review and its underlying trials. Last reviewed September 2026 Beta-sitosterol doesn’t get the same attention as saw palmetto in most prostate-support marketing, but its evidence base is,…
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Vitamin K2 and Testosterone: The Human vs. Animal Evidence Gap
Vitamin K2 and Testosterone: The Human vs. Animal Evidence Gap Source Study Verified Zero Human Trials Found Written by the Health Supplements Lab Editorial Team. We traced the specific citation behind this claim back to its original source. Last reviewed September 2026 “Vitamin K2 boosts testosterone” shows up in enough testosterone supplement marketing that it…
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Indole-3-Carbinol and Estrogen Balance: What the Research Actually Measures
Indole-3-Carbinol and Estrogen Balance: What the Research Actually Measures Real Human Mechanism Study 1 Product Uses It Written by the Health Supplements Lab Editorial Team, drawing on the original human mechanism studies behind this ingredient. Last reviewed September 2026 Indole-3-Carbinol (I3C) is a genuinely unusual ingredient to find in a testosterone product — it doesn’t…
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Panax Ginseng and Erectile Function: The Strongest Natural Evidence We’ve Found
Panax Ginseng and Erectile Function: The Strongest Natural Evidence We’ve Found 7 RCTs Meta-Analyzed 2 Reviewed Products Contain It Written by the Health Supplements Lab Editorial Team, based on a systematic review and meta-analysis published in the British Journal of Clinical Pharmacology. Last reviewed September 2026 Most of our ingredient guides end up correcting an…
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HMB and Betaine
HMB and Betaine: Two Testosterone-Adjacent Ingredients Almost No Product We’ve Reviewed Actually Uses 2025 Meta-Analysis Reviewed 712 Participants Pooled Written by the Health Supplements Lab Editorial Team, drawing on a 2025 GRADE-assessed meta-analysis and controlled trials on betaine. Last reviewed September 2026 A 2023 review study concluded that most testosterone-boosting supplement ingredients don’t produce a…